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Gene Expression Reagents Markets

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Price:
$1,999.00
Publication Date:
April 2007; Pages: 113
File Type:
Downloadable PDF


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The area of gene expression reagents is one of the newest and most important sectors of pharmaceutical and bioscience research and development. The term gene expression reagents refers to chemicals that are used in gene expression experiments that are performed to determine whether a particular gene is expressed--i.e., present--and in some cases at what levels, in a biological sample. The purpose of this TriMark Publications report is to describe the specific segments of the global gene expression reagents market. Within this area, the study covers those segments that are highly active in terms of innovation and growth. Specifically, this review examines the markets for gene expression reagents and small lab equipment all the way up to highly automated platforms. Emphasis is on those companies that are actively developing and marketing gene expression reagents for genomics research in the academic sector and the pharmaceutical, bioscience industry. This study concentrates on the laboratory reagent market segment and the companion gene expression reagents sector in the U.S. and around the world that use materials for genetic research. Particular attention is paid to those areas of the gene expression reagents sector that are showing the greatest growth or the most innovation.

 

TABLE OF CONTENTS

1. Overview 5
1.1 Objectives of the Report 5
1.2 Methodology 6
1.3 Scope of the Report 7
1.4 Executive Summary 7

2. Gene Expression 9
2.1 The Genomics Revolution 9
2.2 Basic Principles of Gene Expression 9
2.3.1 Quantitative Real-Time PCR (qRT-PCR) 10
2.3.2 PCR Labeling Chemistries 11
2.3.3 TaqMan Probes 11
2.3.4 SYBR Green 11
2.4 Microarray Technology 12
2.5 Microarray Target Preparation and Hybridization 12
2.6 RNA Sample Preparation and Assessment 13

3. Gene Expression Reagents 15
3.1 Kit Format vs. Home-Brew Assays 15
3.2 Whole Product Solutions 15
3.3 Emerging Technologies 16

4. Market Environment 17
4.1 Institutional and Government Budgeting 17
4.2 Worldwide Investment in Genomics Technologies and Research 17
4.3 Industry Consolidation and Acquisitions 18

5. Market Drivers 19
5.1 Improved Assay Performance 19
5.2 Cost Effective Systems 19
5.3 Automation 21
5.4 Bioinformatics Solutions 21

6. Worldwide Market for Gene Expression Reagents 23
6.1 Life Science Research 23
6.2 Drug Discovery and Development, Molecular Diagnostics 23
6.3 Commercial Production 23
6.4 Gene Expression Market Size 23
6.4.1 Real-Time PCR Revenue 25
6.4.2 Commercial Microarray Revenue 25
6.4.3 RNA Sample Preparation Revenue 26
6.5 Gene Expression Reagent Market by Region 26
6.6 Users of Gene Expression Products 27
6.6.1 Core Laboratories 28
6.6.2 Consortia 28
6.6.3 Pharmaceutical and Biotechnology Companies 28
6.7 Affiliation 28
6.8 Job Function and Decision Makers 29

7. Key Applications 32
7.1 BioMarker Identification and Pharmacogenomics 32
7.2 Toxicogenomics 32
7.3 Molecular Diagnostics 32

8. Vendor and Product Selection 33
8.1 Product Adoption 33
8.2 Drivers for Product Switching 34

9. Leading Vendors 35

10. Marketing Strategies 38
10.1 e-Marketing and e-Commerce 38
10.2 Catalog 38
10.3 On-Site Cabinet Programs 39

11. Pricing Strategies 40
11.1 Price Elasticity 40
11.2 Strategies 41

12. Distribution Channels 43

13. Competitive Situation 44

14. Opportunities 47

15. Market Strategy Profiles, Leading and Selected Vendors 48
15.1 Applied Biosystems 48
15.1.1 Applera Corporation-Corporate History and Structure 48
15.1.2 Molecular Biology Technology and Products 49
15.1.3 Acquisitions, Partnerships and Collaborations, 2006 50
15.1.4 Product Portfolio Summary 50
15.1.5 Real-Time PCR/Genomics Products and Consumables 51
15.1.6 Real-Time PCR/Genomics New Product Introductions, 2006 51
15.1.7 End-Users 51
15.1.8 Distribution Channels 52
15.1.9 Competition-Gene Expression Products 52
15.1.10 Competitive Analysis 52
15.1.11 Business Model 52
15.2 Affymetrix 53
15.2.1 Corporate History and Structure 53
15.2.2 Technology 54
15.2.3 Partnerships and Collaborations 54
15.2.4 Product Portfolio Summary 55
15.2.5 Complementary Services 56
15.2.6 New Product Introductions 57
15.2.7 End-Users 57
15.2.8 Distribution Channels 57
15.2.9 Competition 58
15.2.10 Competitive Analysis 58
15.2.11 Business Model 58
15.3 Invitrogen 59
15.3.1 Corporate History and Structure 59
15.3.2 Technology 59
15.3.3 Acquisitions 60
15.3.4 Partnerships and Collaborations 61
15.3.5 Product Profile Summary 61
15.3.6 Gene Expression Product Portfolio 63
15.3.7 New Product Introductions 64
15.3.8 End-Users 64
15.3.9 Distribution Channels 65
15.3.10 Competition 65
15.3.11 Competitive Analysis 65
15.3.12 Business Model 65
15.4 Qiagen 66
15.4.1 Corporate History and Structure 66
15.4.2 Technology 67
15.4.3 Acquisitions, Partnerships and Collaborations 67
15.4.4 Collaborations and Partnerships 68
15.4.5 Product Portfolio Summary 68
15.4.6 Complementary Services 69
15.4.7 New Product Introductions 69
15.4.8 End-Users 70
15.4.9 Distribution Channels 70
15.4.10 Competition 70
15.4.11 Competitive Analysis 70
15.4.12 Business Model 71
15.5 GE Healthcare (Formerly Amersham Biosciences) 71
15.5.1 Corporate History and Structure 71
15.5.2 Technology 72
15.5.3 Product Portfolio Summary 73
15.5.4 Complementary Services 75
15.5.5 Genomics New Product Introductions 75
15.5.6 Amersham Biosciences End-Users 75
15.5.7 Distribution Channels 75
15.5.8 Competition 75
15.5.9 Competitive Analysis 75
15.5.10 Business Model 76
15.6 Stratagene 76
15.6.1 Corporate History and Structure 76
15.6.2 Technology 77
15.6.3 Acquisitions, Collaborations, Alliances and Partnerships 78
15.6.4 Product Portfolio Summary-Research Products Division 78
15.6.5 New Product Introductions 79
15.6.6 Complementary Services 79
15.6.7 End-Users 80
15.6.8 Distribution Channels 80
15.6.9 Competition 80
15.6.10 Competitive Analysis 80
15.6.11 Business Model 81

Appendix I: Leading Vendor's Gene Expression Products 82
Appendix II: Gene Expression Product Groups 92
Appendix III: Companies Offering Gene Expression Products 93


LIST OF FIGURES

Figure 2.1: Gene Expression Process 9
Figure 2.2: qRT-PCR Workflow 11
Figure 2.3: Microarray Workflow 13
Figure 6.1: Gene Expression Market by Region 26
Figure 6.2: Researchers Using Gene Expression Technologies Worldwide, 2005 27
Figure 6.3: Distribution of Laboratory Workers by Organization in North America 29
Figure 6.4: Laboratory Job Function 29
Figure 6.5: Product Selection and Purchasing Decision Makers 30


LIST OF TABLES

Table 5.1: Microarray Analysis Cost per Sample 20
Table 5.2: Cost of qRT-PCR Research Reagents and Systems 20
Table 6.1: Five-Year Forecast-Gene Expression Reagents, Instruments 24
Table 6.2: RNA Sample Preparation Revenue 24
Table 6.3: Forecasted Annual Revenue-qRT-PCR, 2005-2010 24
Table 6.4: Forecasted Annual Revenue-Commercial Microarrays, Reagents, Instruments, 2005-2010 24
Table 6.5: Forecasted Annual Revenue-Gene Expression Reagents, Instruments, 2005-2010 25
Table 6.6: Forecasted Annual Revenue-RNA Sample Preparation, 2005-2010 25
Table 6.7: Projected Revenue Growth of Microarrays and Related Products 26
Table 6.8: Major Players' Distribution of Revenue by Region, 2005 27
Table 6.9: Decision Makers Profile 31
Table 9.1: Major Vendors-Gene Expression Reagents and RNA Sample Preparation 35
Table 9.2: Vendors' Key Statistics, 2005 36
Table 9.3: Vendors' Technology and Products 36
Table 11.1: RNA Sample Preparation-Vendors Prices 40
Table 11.2: qPCR Kits-Vendor's Prices 41
Table 11.3: Reverse Transcriptase-Vendor's Prices 42
Table 12.1: Distribution Channels 43
Table 15.1: Applied Biosystems Revenue, 2005 48
Table 15.2: Affymetrix Revenue, 2005 53
Table 15.3: Invitrogen Revenue, 2005 59
Table 15.4: Qiagen Revenue, 2005 67
Table 15.5: GE Healthcare Revenue, 2005 72
Table 15.6: Stratagene Revenue, 2005 77

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